Reactive oxygen species (ROS) are involved in unleashing and aggravating various human pathologies. The association between non-enzymatic antioxidative capacity and serum levels of oxidative stress markers (advanced oxidation protein products, lipoperoxidation, reduction in thiol groups) are a good measure of an organism's oxidative status. It is known that in end stage renal disease (ESRD) oxidative stress increases, but there is no conclusive information concerning differences between hemodialysis and peritoneal dialysis.
In this work, we compared the antioxidative and oxidative stress capacity of plasma in ESRD patients under dialysis treatment in two modalities: peritoneal dialysis (PD) and hemodialysis (HD), compared against apparently healthy controls.
617 patients with ESRD
205 healthy subjects
Pro-oxidants
Antioxidants
Others
See figure 2 and 3
This study was supported by the Consejo Nacional de Ciencia y Tecnología (CONACyT) No. 115403, and Instituto Mexicano del Seguro Social granted to JMG.
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